Professional bio

My name is Patrick Wanner. I am an anesthetist-intensivist and clinical researcher specializing in perioperative and intensive care medicine. Three things drive my work: caring for critically ill patients, finding ways to make acute care safer, and helping younger colleagues discover the beauty of anesthesia, emergency medicine, and critical care.

I completed my residencies in Anesthesiology and Intensive Care Medicine at several Swiss institutions: Kantonsspital St. Gallen, Kantonsspital Baden, and University Hospital Basel. This gave me broad experience in perioperative care, critical care, and both prehospital and in-hospital emergency medicine. I have worked as a prehospital emergency physician for Swiss Air-Rescue (REGA) and for the St. Gallen and Basel ambulance services. Since 2024, I have been a staff physician in Anesthesiology and Critical Care at University Hospital Basel. I am currently pursuing a fellowship in Trauma Anesthesiology at Sunnybrook Health Sciences Centre in Toronto to deepen my expertise in managing critically ill trauma patients.

My research focuses on improving care for high-risk surgical and critically ill patients. I have gained extensive clinical research experience under the mentorship of Prof. Miodrag Filipovic (Kantonsspital St. Gallen / University of Basel), Prof. Luzius A. Steiner (University Hospital Basel / University of Basel), and Prof. PJ Devereaux (Population Health Research Institute / McMaster University). Convinced that both research and patient care need to become far more personalized, I co-founded the Personalising Acute Care Network, a collaborative network that advances the research and adoption of precision acute care medicine. I also lead AUTOREGULATE-NONCARDIAC (NCT05336864), a multicenter prospective cohort study of precision blood pressure monitoring during and after major noncardiac surgery. As part of my Master’s in Health Research Methodology at McMaster University, I am exploring how machine learning can predict clinical deterioration in the perioperative setting.

Teaching and mentoring are a regular part of my work. I am a tutor in the Faculty of Medicine at the University of Basel, a mentor in the Joint Medical Master Program of the Universities of St. Gallen and Zurich, and an Advanced Trauma Life Support (ATLS) instructor.

Current positionS

• Clinical Fellow, Trauma Anesthesiology, Sunnybrook Health Sciences Centre, Toronto, Canada

• Staff Physician and Clinical Researcher, Anesthesiology, University Hospital of Basel, Switzerland

• Investigator, Anesthesiology, Perioperative Medicine, and Surgical Research Group, Population Health Research Institute (PHRI), Hamilton, Canada

Recent positionS

• Staff Physician, Critical Care, University Hospital of Basel, Switzerland

• Research Fellow under the mentorship of Prof. PJ Devereaux at the Population Health Research Institute (PHRI), Hamilton, Canada

• Research Fellow under the mentorship of Prof. Luzius A. Steiner at the University Hospital of Basel, Switzerland

Interests

CLINICAL

• Management and resuscitation of the critically ill in all clinical contexts (prehospital, ED, ICU, OR)

RESEARCH

• Precision medicine in intensive care and perioperative medicine with a focus on precision hemodynamic management

• Leveraging large datasets, machine learning and AI in acute care medicine

Clinical training

• Clinical Fellowship, Trauma Anesthesiology, Sunnybrook Health Sciences Centre, Toronto, Canada (underway)

• Swiss FMH Board Certification in Anesthesiology

• Swiss FMH Board Certification in Intensive Care Medicine

• Prehospital Emergency Medicine (Swiss Society of Emergency and Rescue Medicine) [Fähigkeitsausweis Präklinische Notfallmedizin / Notarzt SGNOR]

Research training

• MSc studies in Health Research Methodology, McMaster University (underway)

• Research Fellowship under mentorship of Prof. PJ Devereaux, Population Health Research Institute

• Advanced Course in Epidemiological Analysis, London School of Hygiene & Tropical Medicine

Teaching & Mentoring

• Tutor for Tutorials of Scientific & Clinical Reasoning, Medical Faculty, University of Basel

• Instructor Advanced Trauma Life Support

• Mentor Joint Medical Master University of St. Gallen / University of Zurich

Academic activity

Research Networks

• The Personalising Acute Care Network

Research projects

• Association of intraoperative blood pressure excursions below cerebral autoregulatory boundaries with organ injury following major noncardiac surgery (AUTOREGULATE-NONCARDIAC) [NCT05336864]

• Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery (The BBB Study) [NCT02533128]

Research Grants

• Kantonsspital St.Gallen Research Commission: The role of cerebral autoregulation monitoring following major noncardiac surgery – a substudy of the AUTOREGULATE-NONCARDIAC study. [Co-Applicant]

• Swiss Society for Anaesthesiology and Perioperative Medicine (SSAPM) Research Grant: Association of intraoperative blood pressure excursions below cerebral autoregulatory boundaries with organ injury following major noncardiac surgery (AUTOREGULATE-NONCARDIAC). [Principal Applicant]

• Canadian Institutes of Health Research: NeuroVISION-2 Study: Neurological Impact of CerebroVascular Events In Noncardiac Surgery Patients. [Co-Applicant]

• Swiss Heart Foundation Research Grant: Biomarkers, Blood Pressure and BIS: Perioperative risk stratification and management optimization of patients at cardiac risk undergoing major noncardiac surgery (The BBB Study). [Principal Applicant]

Research AWARDS

• Best Paper Award 2022 Swiss Society for Anaesthesiology and Perioperative Medicine (SSAPM): Targeting higher intraoperative blood pressures does not reduce adverse cardiovascular events following noncardiac surgery.

Reviewing activity

• Assistant Editor at the European Journal of Anaesthesiology

• Reviewing activity for Anesthesiology, Journal of Clinical Anesthesia, Nature Scientific Reports, CJC Open

PUBLICATIONS

• Gross M, Schindler C, Vogt AP, et al. Study protocol: Feasibility and clinical implications of real-time cerebral autoregulation monitoring in major noncardiac surgery with the Medtronic Cotrending algorithm (AUTOREGULATE-NONCARDIAC-COTRENDING). medRxiv 2026;2026.06.11.26355429. [preprint]

• Wanner PM, Schindler C, Beqiri E, et al. Clinical implications and feasibility of cerebral autoregulation-based precision blood pressure monitoring in major noncardiac surgery - A protocol for AUTOREGULATE-NONCARDIAC, a multicentre prospective cohort study and perioperative precision medicine platform. Eur J Anaesthesiol Intensive Care Med. 2026; 5:1(e0093).

• Wildhaber PO *, Wanner PM *, et al. Impact of staff education on the burden of hypotension during major noncardiac surgery. Br J Anaesth 2024; 133: 671–4.

• Kowalik K, Silverman M, Oraii A, et al. Landiolol for perioperative atrial tachyarrhythmias in cardiac and thoracic surgery patients: a systematic review and meta-analysis. Br J Anaesth 2024; 133: 222–5.

• Stroda A, Mauermann E, Ionescu D, et al. Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study. Br J Anaesth 2024; 132: 675–84 [Collaborator]

• Roth S, M’Pembele R, Nienhaus J, et al. Association between self-reported functional capacity and general postoperative complications: analysis of predefined outcomes of the MET-REPAIR international cohort study. Br J Anaesth 2024; 132: 811–4 [Collaborator]

• Wanner PM, Vogt AP, Filipovic M, Steiner LA, Personalising Acute Care Network. Intraoperative hypotension and postoperative outcomes: just the tip of the iceberg. Comment on Br J Anaesth 2023; 131: 823–31. Br J Anaesth 2024; 132: 804–5

• Wanner PM, Filipovic M. Intraoperative hypotension: New answers, but the same old questions. J Clin Anesth. 2024. In press.

• Lurati Buse GA, Mauermann E, Ionescu D, et al. Risk assessment for major adverse cardiovascular events after noncardiac surgery using self-reported functional capacity: international prospective cohort study. Br J Anaesth. Jun 2023;130(6):655-665. doi:10.1016/j.bja.2023.02.030 [Collaborator]

• Wanner PM, Wulff DU, Djurdjevic M, Korte W, Schnider TW, Filipovic M. Targeting higher intraoperative blood pressures does not reduce adverse cardiovascular events following noncardiac surgery. J Am Coll Cardiol. 2021;78:1753-1764.

• Wanner PM, Filipovic M. The Right Ventricle—You May Forget it, but It Will Not Forget You. J. Clin. Med. 2020, 9, 432.

• Kindler M, Wanner PM, Filipovic M. Cardiac risk in non-cardiac surgery: A review, Trends in Anaesthesia and Critical Care. 2018, https://doi.org/10.1016/j.tacc.2018.04.013.

• Yurttas T, Wanner PM, Filipovic M. Perioperative management of antithrombotic therapies. Curr Opin Anaesthesiol 2017.

• Bettex DA, Wanner PM, Bosshart M, et al. Role of sevoflurane in organ protection during cardiac surgery in children: a randomized controlled trial. Interactive CardioVascular and Thoracic Surgery Oxford University Press; 2014;:ivu381

Book chapters

• Murgatroyd Wiles AJ, Steiner LA, Wanner PM. Brain tissue oxygenation in Neuromonitoring Techniques, 2ed, Elsevier, In press.

• Wanner PM, Meyfroidt G, Steiner LA. Sedation & Analgesia. In: Oxford Textbook of Neurocritical Care, 2ed, Oxford University Press.

• Wanner PM, Yurttas T, Filipovic M. Intraoperative Management and Its Influence on Postoperative Biomarker Release. In: Biomarkers in Trauma, Injury and Critical Care. Springer. 2022.

• Yurttas T, Wanner PM, Filipovic M. Therapeutic Strategies in Patients with Postoperative Elevation of Cardiac Biomarkers. In: Biomarkers in Trauma, Injury and Critical Care. Springer. 2022.

• Gomes NV, Wanner PM, Goettel N. Newer brain monitoring techniques. In: Prabhakar, ed: Essentials of Evidence-Based Practice in Neuroanesthesia and Neurocritical Care. Elsevier. 2022.

• Wanner PM, Filipovic M. Der rechte Ventrikel - das Wichtigste für den Intensivmediziner. In: Eckart, Forst, Briegel, eds.: Intensivmedizin. Kompendium und Repetitorium zur interdisziplinären Weiter- und Fortbildung. ecomed Verlagsgesellschaft AG & Co. KG, Landsberg. 2018.

PRESENTATIONS

• Perioperative hemodynamic management - Past, Present, Future, Grand Rounds December 2025, Kantonsspital Aarau, Switzerland

• Perioperative management of antihypertensive drugs, Refresher Course, SwissAnaesthesia 2025, Lausanne, Switzerland

• Wieviel Blutdruck braucht der Mensch? [How much blood pressure do humans need?], Herbstsymposium Anästhesiepflege 2025, University Hospital Basel

• Perioperatives hämodynamisches Management [Perioperative hemodynamic management] - Past, Present, Future. 78. St. Galler Anästhesiesymposium 2024, St. Gallen, Switzerland

• Why did blood pressure management not work? And what's next? Korean Society of Cardiothoracic and Vascular Anesthesiologists (KSCTVA) Annual Meeting 2023, Seoul, South Korea

• Intraoperative MAPs of 60 or greater versus 75 or greater, Perioperative Care Congress 2022, Society for Perioperative Research and Care / McMaster University, Canada

• Just The Tip Of The Iceberg - Perioperatives Blutdruckmanagement [Perioperative Blood Pressure Management], 67. St. Galler Anästhesie- und Intensivsymposium 2022, St. Gallen, Switzerland

• Raising Blood Pressure in Major Noncardiac Surgery, Poster & Free Communication Presentation, Swiss Society for Anaesthesiology & Resuscitation, Annual Meeting 2019, Interlaken, Switzerland

• Role of Volatile Anesthetics in Organ Protection during Cardiac Surgery in Children, Poster presentation, Society of Cardiovascular Anesthesiologists, 35th Annual Meeting 2013, Miami USA

INTERVIEWS

• Intraoperative Hypotension: Marker or Mediator of Disease? Medscape, October 25 2021

For more information, please contact me by email using the form on the contact page.